People with the Multiple Sclerosis (MS) suffer from vitamin D deficiency. Low level of vitamin D is related to development of MS disease. MS patients with low level of vitamin D are prone to more disability and a higher degree of MS activity. Vitamin D is essential for bone health and regulation of immune system.


In this pilot study, the effect of low dose colecalciferol (LDC) and high dse ergocalciferol (HDE) on the Vitamin D levels in people with MS has been studied. Vitamin D levels of 40 MS patients were evaluated, who took either LDC or HDE.


The large number of MS patients were vitamin D deficient and the HDE increased noticeably the level of vitamin D. HDE was more efficient than LDC in increasing vitamin D level.

Although the researchers are still investigating the required daily amount of vitamin D for people with MS, but so far it is recommended a daily supplement of 40-60 nanograms per milliliter (ng/mL) vitamin D.